F2-RNA Pull-Down Kit (Animal), SKU: 8701
 
Product Description
The independently developed F2-RNA Pull-Down Kit utilizes a proprietary 16nt RNA tag ("F2") to label target RNA. By employing specific ligand-conjugated magnetic beads, the kit efficiently captures the target F2-RNA along with its associated proteins or RNAs. The F2 tag is a short sequence that maintains the native structure and function of the target RNA, making it suitable for labeling all RNA types.
 
F2-RNA Pull-Down Kit
 
The "RNA-First" Approach
Purpose: To identify the Proteins (RNA-binding proteins) or other RNAs that interact with a specific RNA of Interest (ROI).
Technical Advantage (The F2 Tag): Instead of using bulky Biotin-Streptavidin systems—which often suffer from high background noise due to endogenous biotin in animal tissues—this kit uses a proprietary 16nt F2 RNA tag.
Impact: The F2 tag is small enough to maintain the native folding and secondary structure of the target RNA. This ensures that the proteins captured are biologically relevant and not artifacts of a misfolded RNA probe.
 
Product Manual
F2-RNA Pull-Down Kit (Animal) CAN