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Lipomaster 3000 Transfection Reagent, SKU: TL301
Lipomaster 3000 Transfection Reagent, SKU: TL301
Third-generation liposome transfection reagent for difficult-to-transfect cells
 
PRODUCT OVERVIEW
 
Lipomaster 3000 transfection reagent is a liposome-mediated transfection reagent suitable for transfecting plasmid DNA and RNA into various adherent or suspension cells.

The Lipomaster 3000 transfection reagent has a well-defined structure, enabling highly efficient and reproducible cell transfection. The T3000 enhancer acts as a transfection enhancer, promoting rapid DNA entry into the cell nucleus. The combination of these two reagents significantly improves the transfection efficiency of large plasmid fragments and difficult-to-transfect cells.
 
Lipomaster 3000 Transfection Reagent has the excellent ability to form liposome/nucleic acid complexes and rapid release of nucleic acid transfected into cells, which ensures excellent transfection performance and extremely low cytotoxicity.
 
The presence of serum and antibiotics does not affect its transfection effect, so the formed liposome/nucleic acid complex can be directly added to the complete medium.
 
Components
See Table above.
     
    Product Manual
    Manual_TL301 V23.1
     
    Citation
    97/100 Bioz Rating, 100 Citations  by May 10, 2026.  See the updated citation link. 
     
    Highlight:
    1. Intracellular sclerostin promotes tumor progression and metastasis as a potential therapeutic target in triple-negative breast cancer.
    Meiheng Sun, Hang Luo, ..., Ge Zhang
    Cell Reports Medicine, 2026 Apr 23,  DOI: 10.1016/j.xcrm.2026.102763  
    2. A non-coding variant at 2p24.2 confers susceptibility to non-syndromic cleft lip and palate through LLPS-dependent regulation of MYCN
    Wu Zhaoyi, Yuan Zhiying, ..., He Miao
    3. Counteracting FOX proteins epigenetically control the herpesvirus lytic-latent balance
    Yuhang Xiang, Xiyuan Yang, ..., Dongli Pan
    Nature Communications, 2026 Feb 02. https://www.nature.com/articles/s41467-026-68915-1 
    4. Adipocytic sclerostin loop3-LRP4 interaction required by sclerostin to impair whole-body lipid and glucose metabolism.
    Hewen Jiang, Xiaohui Tao, ..., Bao-Ting Zhang
    Nature communications, 2026 Jan 16, https://www.nature.com/articles/s41467-026-68526-w
    5. EGR Proteins Mediate Interferon-Independent Anti-HSV-1 Responses Through Viral and Host Targets.
    Shuaishuai Wang, Fujun Hou, ..., Dongli Pan
    Advanced Science, 2026 Jan 04, https://doi.org/10.1002/advs.202515546  
    6. Spatial control of m 6 A deposition on enhancer and promoter RNAs through co-acetylation of METTL3 and H3K27 on chromatin.
    Xiang Huang, Jie Zhang, ..., Jinkai Wang
    Molecular Cell,  2025 May 13, 85(7):1349-1365.e10. doi: 10.1016/j.molcel.2025.02.016 
     
     

    Lipomaster 3000 Transfection Reagent, SKU: TL301

    SKU: TL301-01
    CA$826.00Price
    Quantity

    • Highlights

       

       

       

       

      Features  

      • Superior transfection efficiency: Works for large plasmids & difficult-to-transfect cells.

       

      • Broad compatibility: Only one reagent can be used for transfection of plasmid DNA, mRNA, siRNA, and co-transfection, etc, and be applicable for adherent or suspension cells with extremely low cytotoxicity.

       

      • Serum and antibiotics does not affect transfection effect: Formed liposome/nucleic acid complex can be directly added to the complete medium.

       

      Applications

      1. Cell types transfected with TL301: 293T, A549, BHT101, BRL-3a, BSR-T7, C2C12, COS7, DF1, H9C2(2-1), HaCaT, HCT116, Hela, Hepg2, HEK-293T, HL-02, HUH7,IPEC-J2, Jurkat, K562, MA-104, MC38, MC3T3-E1, MCF-7, MDA_MB_231, MDCK, NCI-H1299, NCI-H929, NIH3T3, NSCLC, PC-3, PC9/GR, PK15, RAW264.7, SNU387, U87mg, Vero
      2. TL301-Lipid-based lentivirus transfection workflow diagram. See figure above.

       

       

    • Storage

      Store a 2 ~ 8°C. 

      Adjust the shipping method according to the destination.

    • Note

      Please invert this product upside down several times to mix thoroughly before each use. Do not freeze.

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